Purine synthesis: which amino acid is a precursor for the nucleotide bases adenine and guanine?
Glutamine plays a crucial role in the biosynthesis of purines, which are vital components of nucleic acids (DNA and RNA). It acts as a nitrogen donor in the synthesis of the nucleotide bases adenine and guanine. This process is essential for the production of ATP, GTP, and other nucleotides that are fundamental for cellular energy, protein synthesis, and cell division. Without glutamine’s contribution to purine synthesis, the body would struggle to maintain adequate levels of these critical nucleotide bases, impacting a wide range of biological processes.
Which amino acid is essential for purine synthesis, acting as a precursor for the nucleotide bases adenine and guanine?
A) Histidine
B) Glutamine
C) Arginine
D) Leucine
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