This video shows the surgical technique for neonatal repair of Interrupted Aortic Arch and Ventricular Septal Defect. This is a rare congenital heart birth defect. We performed a primary anastomosis of the descending thoracic aorta to the ascending aorta, and a native pericardial patch repair of the Ventricular Septal Defect. The video shows the actual operative technique, and the day by day postoperative recovery, managed by dedicated pediatric cardiac anesthesia, nursing and intensive care teams.