Systems Genetics - Lecture 14 - Deep Learning in Life Sciences (Spring 2021)

MIT Spring 2021 Prof. Manolis Kellis Deep Learning in the Life Sciences / Computational Systems Biology Playlist: Latest slides and course today: Spring 2021 slides and materials: 00:00 Review 04:30 Linear mixed models 13:10 Heritability 16:02 Defining hg2 20:21 Stratified LD score regression 41:20 Application to chromatin and gene expression data 52:36 Decomposition of genetic associations 1:05:15 Experiments of nature 1:09:57 Polygenic risk models