TMS and Autism – 2021 Research Updates

Learn research updates about transcranial magnetic stimulation and autism. This is a joint presentation by The World Autism Organisation and The Autism Research Institute. Note: The research presentation begins at 12:10. Free certificates of participation are available upon successful completion of a brief knowledge quiz at Manuel Casanova, MD, served on the founding board of the National Alliance for Autism Research (now Autism Speaks) and the Autism Tissue Board. He has served on the Board of Directors or Scientific Advisory Board of numerous organizations including the Autism Research Institute. His research has been recognized by a EUREKA award from the NIMH for the introduction of repetitive Transcranial Magnetic Stimulation (rTMS) in the therapy of autism spectrum disorders. __ 0:00 - First co-sponsored webinar with ARI and World Autism Organization 12:00 - Autism as a neurodevelopmental disease 16:20 - Development of cerebral cortex 19:50 - Disorders of neuronal migration in autism  20:35 - Study: Neuropathological markers in autism 21:10 - Mini-columns 23:09 - Compartmentalization of mini-columns in autism 24:57 - Shower Curtain of Inhibition| 27:58 - Study: Hat models of inhibitory deficit in autism 33:46 - Interneurons: Calcium-binding proteins  35:50 - PV-positive cells in controls and autism  38:00 - Implications of gamma oscillations in autism 41:10 - Gamma oscillations and EEGs 43:30 - TMS and Faraday’s Law 45:04 - Transcranial Magnetic Stimulation (TMS) 47:30 - TMS and the dorsolateral prefrontal cortex (DLPC) 47:53 - Clinical trial protocol and study design examples 50:29 - Effects of rTMS on gamma oscillations in autism and clinical significance  52:14 - Studies: 1) Post-TMS changes in response time and 2) Error rate and post-error rate improvement 55:40 - Heart Rhythm: Temporal and Frequency analysis 57:55 - Study: Effects of 18 TMS sessions on autonomic functions in ASD 59:20 - Studies: 1)TMS in autism: Repetitive and aberrant behaviors and 2) Effect of TMS sessions and behaviors 1:00:00 - Study: TMS in autism: Neurofeedback 1:01:00 - TMS in the public press 1:02:35 - Closing points 1:03:58 - Question & Answer session