How Heme group is held in place in the Hemoglobin?

An adult at rest consumes the equivalent of 250 ml of pure oxygen per minute. This oxygen is used to provide energy for all the tissues and organs of the body, even when the body is at rest. The body’s oxygen needs increase dramatically during exercise or other strenuous activities. The oxygen is carried in the blood from the lungs to the tissues where it is consumed. However, only about 1.5% of the oxygen transported in the blood is dissolved directly in the blood plasma. Transporting the large amount of oxygen required by the body, and allowing it to leave the blood when it reaches the tissues that demand the most oxygen, require a more sophisticated mechanism than simply dissolving the gas in the blood. To meet this challenge, the body is equipped with a finely-tuned transport system that centers on the metal complex heme. Keywords: The iron atom is held in place by direct contact with: A) Carboxyl groups in heme B) Nitrogens in heme C) Carbons in heme D) Sulfur atoms in cysteines E) Nitrogen atoms in histidines F) Oxygen atoms in histidines #heme #hemoglobin #erethrocyte #protein #Histidine #covalentBound #coordinatecovalentBonds #blood