Mechanism of Anthrax Toxins

Protein Lounge animations @ Anthrax is an acute infectious disease caused by the spore-forming gram positive, aerobic bacterium Bacillus anthracis, whose pathogenesis is primarily the result of a tripartite toxin. This toxin is composed of three proteins: the Protective Antigen (PA), the Edema Factor (EF) and the Lethal Factor (LF). These proteins work together to enter a cell and disrupt the signaling pathways. Secreted from the bacteria as nontoxic mo