Simple Mendelian genetics problem and solution

Huntington’s disease is an inherited disease that causes the progressive breakdown (degeneration) of nerve cells in the brain. Huntington’s disease has a broad impact on a person’s functional abilities and usually results in movement, thinking (cognitive) and psychiatric disorders. Most people with Huntington’s disease develop signs and symptoms in their 40s or 50s, but the onset of disease may be earlier or later in life. When disease onset begins before age 20, the condition is called juvenile Huntington’s disease. Earlier onset often results in a somewhat different presentation of symptoms and faster disease progression. Medications are available to help manage the symptoms of Huntington’s disease, but treatments can’t prevent the physical, mental and behavioral decline associated with the condition. Huntington’s disease usually causes movement, cognitive and psychiatric disorders with a wide spectrum of signs and symptoms. Which symptoms appear first varies greatly among affected people. During the course of the disease, some disorders appear to be more dominant or have a greater effect on functional ability. Movement disorders The movement disorders associated with Huntington’s disease can include both involuntary movements and impairments in voluntary movements: Involuntary jerking or writhing movements (chorea) Involuntary, sustained contracture of muscles (dystonia) Muscle rigidity Slow, uncoordinated fine movements Slow or abnormal eye movements Impaired gait, posture and balance Difficulty with the physical production of speech Difficulty swallowing Impairments in voluntary movements — rather than the involuntary movements — may have a greater impact on a person’s ability to work, perform daily activities, communicate and remain independent. #gene #protein #genomes #Genetics #DNA #chromosome #Allele #locus #GeneStructure #GeneticsLecture #Cancer #Genetics101 #Eukaryotic #Prokaryotes #alleles #GeneticExamQuestionsSolutions #genomics #MolecularBiology #genes #DNAMolecule #Eukaryotes #RNA #genome #Proteins #phenotype #HuntingtonsDisease #genotype #geneExpression #geneticCode #rRNA #GeneticTesting #Chromosomes #GeneticsExamQuestionsSolutions