Pharmacology - CANCER DRUGS – CELL CYCLE SPECIFIC AND NONSPECIFIC AGENTS (MADE EASY)

Cancer is generally defined as the uncontrolled growth of abnormal cells in the body. One of the common approaches in treatment of cancer is to use drugs that target fast-dividing cells at different phases of the cell cycle. This pharmacology lecture covers mechanism of action and side effects of cell cycle specifc agents including topoisomerase inhibitors (type I & type II) and microtubule inhibitors (vinca alkaloids & taxanes) as well as cell cycle nonspecfic agents including antitumor antibiotics (anthra