Find and neutralize: Immunoglobulins vs Coronavirus
The pandemic of the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been posing great threats to the world in many aspects. In order to understand how best to neutralize the enemy, scientists from all over the world had to throw their energy into studying the structure of the virus and its behavior in the human body. We tried to collect the most relevant data on the structure of the coronavirus (2019-nCoV) into one coherent model and show you how the virus enters our cells and who protects us.
On the basis of PDB structures 6y3y, 5x29 and surface modeling we modeled the structure of the coronavirus. Some of the structures were just the models, since we simply could not find some real SARS-CoV-2 proteins in the open access. Nevertheless, we have modeled the most important scene of the binding of spike proteins (6vsb) and their interaction with the ACE2 receptor (6m17) with great precision.
By the way, this is how the coronavirus enters our cells — the spike proteins have an