Large Offspring Syndrome (cloning)

What are the risks associated with animal cloning? Cloned embryos are more likely to be lost during pregnancy than normal embryos, which accounts for the low success rate of cloning. Large Offspring Syndrome can also affect some cloned animals. Animals with LOS have growth defects and are considerably larger at birth than animals resulting from natural Offspring Syndrome is more often found in cloned animals from livestock species, such as sheep, than in other cloned animals. These abnormalities may be caused by the conditions used to grow the cells and embryos in the lab, as well as epigenetic imprinting, which might be improved by future research.