Centromeric Chromatin Transition at Mitotic Onset/ Curr. Biol., July 25, 2019 (Vol. 29, Issue 16)

Centromeres are called to action at cell division, serving as the site on each chromosome where kinetochores are built to attach to the microtubule-based spindle and ultimately mediate proper segregation to the daughter cells. This video highlights new insight from cellular and atomic-level structural studies of a transition in centromeric chromatin at this critical portion of the cell cycle, reported by Allu et al., and integrates it with current models of higher-order mitotic chromosome structure and of k